From Genome Information to Protein Structures and Function.
نویسندگان
چکیده
منابع مشابه
Detecting protein function and protein-protein interactions from genome sequences.
A computational method is proposed for inferring protein interactions from genome sequences on the basis of the observation that some pairs of interacting proteins have homologs in another organism fused into a single protein chain. Searching sequences from many genomes revealed 6809 such putative protein-protein interactions in Escherichia coli and 45,502 in yeast. Many members of these pairs ...
متن کاملPrediction of Structures and Interactions from Genome Information
Predicting three dimensional residue-residue contacts from evolutionary information in protein sequences was attempted already in the early 1990s. However, contact prediction accuracies of methods evaluated in CASP experiments before CASP11 remained quite low, typically with < 20% true positives. Recently, contact prediction has been significantly improved to the level that an accurate three di...
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ژورنال
عنوان ژورنال: Seibutsu Butsuri
سال: 2002
ISSN: 0582-4052,1347-4219
DOI: 10.2142/biophys.42.224